Publications


2018

Roemhild R, Gokhale CS, Dirksen P, Blake C, Rosenstiel P, Traulsen A, Andersson, DI, Schulenburg H (2018) Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy. PNAS September 25, 2018 115 (39) 9767-9772

(Article).

Godfroid M, Dagan T, Kupczok A. Recombination Signal in Mycobacterium tuberculosis Stems from Reference-guided Assemblies and Alignment Artefacts. Genome Biol Evol. 2018 Aug 1;10(8):1920-1926.

(Article).

Walker TM, Merker M, Knoblauch AM, Helbling P, Schoch OD, van der Werf MJ, Kranzer K, Fiebig L, Kröger S, Haas W, Hoffmann H, Indra A, Egli A, Cirillo DM, Robert J, Rogers TR, Groenheit R, Mengshoel AT, Mathys V, Haanperä M, Soolingen DV, Niemann S (equal contribution), Böttger EC, Keller PM; MDR-TB Cluster Consortium. A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study. Lancet Infect Dis 2018 18(4):431-440. doi: 10.1016/S1473-3099(18)30004-5.

Heyckendorf J, Andres S, Köser CU, Olaru ID, Schön T, Sturegård E, Beckert P, Schleusener V, Kohl TA, Hillemann D, Moradigaravand D, Parkhill J, Peacock SJ, Niemann S (equal contribution), Lange C, Merker M. What is resistance? Impact of phenotypic versus molecular drug resistance testing on multi- and extensively drug-resistant tuberculosis therapy. Antimicrob Agents Chemother 2017 pii: AAC.01550-17

Barbosa C, Trebosc V, Kemmer C, Rosenstiel P, Beardmore R, Schulenburg H*, Jansen G* Alternative evolutionary paths to bacterial antibiotic resistance cause distinct collateral effects. Mol. Biol. Evol. 2017; 34:2229-2244. * Shared senior authorship.

Barbosa C, Beardmore R, Schulenburg H*, Jansen G* (2018) Antibiotic combination efficacy (ACE) networks for a Pseudomonas aeruginosa model. PLoS Biol. 16: e2004356. * Shared senior authorship.

Prange R*, Thiedmann M*, Bhandari A, Mishra N, Sinha A, Häsler R, Rosenstiel P, Uliczka K, Wagner C, Yldirim AÖ, Fink C, Roeder T A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expendient target for intervention Aging 2018; 10: 2122-2135. doi: 10.18632/aging.101536.

Romey-Glüsing R*, Li Y*, Hoffmann J, von Frieling J, Knop M, Pfefferkorn R, Bruchhaus I, Fink C, Roeder T Nutritional regimens with periodically recurring phases of dietary restriction extend lifespan in Drosophila. FASEB, 2018; J 32: 1993-2003. doi: 10.1096/fj.201700934R

Reiling N, Homolka S, Kohl TA, Steinhäuser C, Kolbe K, Schütze S, Brandenburg J. Shaping the niche in macrophages: Genetic diversity of the M. tuberculosis complex and its consequences for the infected host. Int J Med Microbiol. 2017 Sep 14. pii: S1438-4221(17)30294-1

Fehrenbach H, Wagner C, Wegmann M. Airway remodeling in asthma: what really matters. Cell Tissue Res. 2017 Mar;367(3):551-569.

Stucki D, Brites D, Jeljeli L (equal contribution), Coscolla M, Liu Q, Trauner A, Fenner L, Rutaihwa L, Borrell S, Luo T, Gao Q, Kato-Maeda M, Ballif M, Egger M, Macedo R, Mardassi H, Moreno M, Vilanova GT, Fyfe J, Globan M, Thomas J, Jamieson F, Guthrie JL, Asante-Poku A, Yeboah-Manu D, Wampande E, Ssengooba W, Joloba M, Boom WH, Basu I, Bower J, Saraiva M, Vasconcellos SE, Suffys P, Koch A, Wilkinson R, Gail-Bekker L, Malla B, Ley SD, Beck HP, de Jong BC, Toit K, Sanchez-Padilla E, Bonnet M, Gil-Brusola A, Frank M, Penlap Beng VN, Eisenach K, Alani I, Ndung'u PW, Revathi G, Gehre F, Akter S, Ntoumi F, Stewart-Isherwood L, Ntinginya NE, Rachow A, Hoelscher M, Cirillo DM, Skenders G, Hoffner S, Bakonyte D, Stakenas P, Diel R, Crudu V, Moldovan O, Al-Hajoj S, Otero L, Barletta F, Carter EJ, Diero L, Supply P, Comas I, Niemann S, Gagneux S. Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages. Nat Genet 2016 48(12):1535-1543

S. Bartel, G. Carraro, F. Alessandrini, S. Krauss-Etschmann, FLM. Ricciardolo, S. Bellusci . miR-142-3p is associated with aberrant WNT signaling during airway remodeling in asthma. Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L328-L333. doi: 10.1152/ajplung.00113.2018

M. Kostric, K. Milger, S. Krauss-Etschmann, M. Engel, G.Vestergaarda, M. Schloter, A. Schöler. Development of a stable lung microbiome in healthy neonatal mice.
Microb Ecol. 2018 75(2):529-542;doi: 10.1007/s00248-017-1068

Dallenga T, Repnik U, Corleis B, Eich J, Reimer R, Griffiths GW, Schaible UE. M. tuberculosis-Induced Necrosis of Infected Neutrophils Promotes Bacterial Growth Following Phagocytosis by Macrophages. Cell Host Microbe. 2017 Oct 11;22(4):519-530.e3. doi: 10.1016/j.chom.2017.09.003.

Belheouane, M., Gupta, Y., Künzel, S., Ibrahim, S. & Baines, J.F. Improved detection of gene-microbe interactions in the mouse skin microbiota using high-resolution QTL mapping of 16S rRNA transcripts. Microbiome 2017; 5, 59

Wang, J., Thingholm, L.B., Skiecevičienė, J., Rausch, P., Kummen, M., Hov, J.R., Degenhardt, F., Heinsen, F.-A., Rühlemann, M.C., Szymczak, S., Holm, K., Esko, T., Sun, J., Pricop-Jeckstadt, M., Al-Dury, S., Bohov, P., Bethune, J., Sommer, F., Ellinghaus, D., Berge, R.K., Hübenthal, M., Koch, M., Schwarz, K., Rimbach, G., Hübbe, P., Pan, W.-H., Sheibani-Tezerji, R., Häsler, R., Rosenstiel, P., D'Amato, M., Cloppenborg-Schmidt, K., Künzel, S., Laudes, M., Marschall, H.-U., Lieb, W., Nöthlings, U., Karlsen, T.H.*, Baines, J.F.* & Franke, A.* Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota. Nature Genetics 2016; 48, 1396-1406

Peuker, K., Muff, S., Wang, J., Künzel, S., Bosse, E., Zeissig, Y., Luzzi, G., Basic, M., Strigli, A., Ulbricht, A., Kasser, A., Arlt, A., Chavakis, T., van den Brink, G.R., Schafmayer, C., Egberts, J.H., Becker, T., Bianchi, M.E., Bleich, A., Röcken, C., Hampe, J., Schreiber, S., Baines, J. F., Blumberg, R.S. & Zeissig, S. Epithelial calcineurin controls microbiota-dependent intestinal tumor development. Nature Medicine 2016; 22, 506-515

2017

Alternative evolutionary paths to bacterial antibiotic resistance cause distinct collateral effects. Barbosa C, Trebosc V, Kemmer C, Rosenstiel P, Beardmore R, Schulenburg H*, Jansen G* (2017) Mol. Biol. Evol. 34:2229-2244 (Article). *Shared senior authorship

(Article).

Airway remodeling in asthma: what reall matters Fehrenbach H, Wagner C, Wegmann M [2017] Cell Tissue Res 2017: 551-569

(Article).

Influences of environmental bacteria and their metabolites on allergies, asthma, and host microbiota.
Jatzlauk G, Bartel S, Heine H, Schloter M, Krauss-Etschmann S.
Allergy. 2017 Dec;72(12):1859-1867. doi: 10.1111/all.13220. Epub 2017 Jun 28. Review.

(Article).

Development of a Stable Lung Microbiome in Healthy Neonatal Mice.
Kostric M, Milger K, Krauss-Etschmann S, Engel M, Vestergaard G, Schloter M, Schöler A.
Microb Ecol. 2017 Sep 13. doi: 10.1007/s00248-017-1068-x. [Epub ahead of print]

(Article).

Identification of a plasma miRNA biomarker-signature for allergic asthma: a translational approach.
K. Milger, J.Götschke, L. Krause, P. Nathan, F. Alessandrini, A. Tufman, R. Fischer, S. Bartel, F. J. Theis, J. Behr, S. Dehmel, N.S. Mueller, N. Kneidinger, S. Krauss-Etschmann.
Allergy 2017 Dec;72(12):1962-1971. doi: 10.1111/all.13205

(Article).

D-tryptophan from probiotic bacteria influences the gut microbiome and allergic airway disease.
Kepert I, Fonseca J, Müller C, Milger K, Hochwind K, Kostric M, Fedoseeva M, Ohnmacht C, Dehmel S, Nathan P, Bartel S, Eickelberg O, Schloter M, Hartmann A, Schmitt-Kopplin P, Krauss-Etschmann S.
J Allergy Clin Immunol. 2017 May;139(5):1525-1535. doi: 10.1016/j.jaci.2016.09.003. Epub 2016 Sep 23.

(Article).

Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma.
Bartel S, Schulz N, Alessandrini F, Schamberger AC, Pagel P, Theis FJ, Milger K, Noessner E, Stick SM, Kicic A, Eickelberg O, Freishtat RJ, Krauss-Etschmann S.
Sci Rep. 2017 Apr 6;7:46026. doi: 10.1038/srep46026.

(Article).

The potential for targeted rewriting of epigenetic marks in COPD as a new therapeutic approach.
Wu DD, Song J, Bartel S, Krauss-Etschmann S, Rots MG, Hylkema MN.

(Article).

2016

Prenatal exposure to tobacco smoke sex dependently influences methylation and mRNA levels of the Igf axis in lungs of mouse offspring.
K. Meyer, S. Krauss-Etschmann, W. Kooistra, M. Reinders-Luinge, W. Timens, L. Kobzik, T. Plösch, M. Hylkema..
AJP Lung Apr 1;312(4):L542-L555. doi: 10.1152/ajplung.00271.2016

(Article).

Association between clinical antibiotic resistance and susceptibility of Pseudomonas in the cystic fibrosis lung.Jansen G, Mahrt N, Tueffers L, Barbosa C, Harjes M, Adolph G, Friedrichs A, Krenz-Weinreich A, Rosenstiel P, Schulenburg H (2016) Association between clinical antibiotic resistance and susceptibility of Pseudomonas in the cystic fibrosis lung. Evol Med Publ Health 2016:182-194

(Article).