Lung disease

© Sebastian Kaulitzki, Fotolia

Leibniz ScienceCampus for Evolutionary Medicine of the Lung

The Leibniz ScienceCampus Evolutionary Medicine of the Lung (EvoLUNG) integrates evolutionary theory into lung research to achieve a better understanding of chronic lung diseases such as tuberculosis, asthma and chronic obstructive pulmonary disease. Three main issues are focused on (1) the spread and evolution of multi-drug resistant pathogens of the lung, (2) the evolutionary origin and possible benefits of disease genes, and (3) the interplay between four key players: disease susceptibility genes, microbiota, pathogens, and abiotic environmental stressors.

The campus partners will create an interdisciplinary research scenery linking competences in evolutionary theory, experimental evolution and evolutionary genomics with functional analysis of disease susceptibility genes, host-microbiota interactions, and chronic inflammatory lung disease.